Saturday, March 18, 2023

Colorectal cancer (CRC)

 Colorectal cancer (CRC) of ascending colon

End Stage Renal Disease (ESRD)

ca marker for colon cancer

Colon cancer and rectal cancer are often grouped together because they have many features in common.(1)

Colorectal cancer screening:  

  1. stool base test -Stool OB: tests – a fecal occult blood test (FOBT) or fecal immunochemical test (FIT) ,Guaiac-based fecal occult blood test (gFOBT)
  2. Visual structure exam: colonoscopy
  3. X Ray: special imaging (x-ray) tests.
  4. Stool DNA test : (2),(3),(4)

blood test (Lab) Blood tests for this tumor marker can sometimes suggest someone might have colorectal cancer, but they can't be used alone to screen for or diagnose cancer.

Tumor markers: Colorectal cancer cells sometimes make substances called tumor markers that can be found in the blood.

Liver enzymes: You may also have a blood test to check your liver function, because colorectal cancer can spread to the liver.


Digital rectal exam (DRE) 


 The most common tumor marker for colorectal cancer is carcinoembryonic antigen (CEA).

What is adenocarcinoma of the colon (or rectum)?

Adenocarcinoma is a type of cancer that starts in the cells that form glands making mucus to lubricate the inside of the colon and rectum. This is the most common type of colon and rectum cancer.Feb 27, 2017 

copy from link : https://www.cancer.org/cancer/colon-rectal-cancer/about/what-is-colorectal-cancer.html

  • The first section is called the ascending colon. It starts with a pouch called the cecum, where undigested food is comes in from the small intestine. It continues upward on the right side of the abdomen (belly).
  • The second section is called the transverse colon. It goes across the body from the right to the left side.
  • The third section is called the descending colon because it descends (travels down) on the left side.
  • The fourth section is called the sigmoid colon because of its “S” shape. The sigmoid colon joins the rectum, which then connects to the anus. 

The ascending and transverse sections together are called the proximal colon. The descending and sigmoid colon are called the distal colon.



Sign and symptom 

  1. Lower gastrointestinal bleeding (LGIB) 


Copy from Link  https://coloncancercoalition.org/get-educated/what-is-colon-cancer/

 The faculty director for a California college’s Office of Equity, Social Justice and Multicultural Education says she’s being terminated after she questioned antiracist “orthodoxy,” objected to the co

tabloid definition

 What makes something a tabloid?

Word forms: tabloids

tab·loid

noun

noun: tabloid; plural noun: tabloids

a newspaper having pages half the size of those of a standard newspaper, typically popular in style and dominated by headlines, photographs, and  sensational stories.

"the tabloid press"

NORTH AMERICAN

sensational in a lurid or vulgar way.

modifier noun: tabloid

"they argued about who made what allegation on what tabloid TV show"

Sample sentences : Love to see someone tackle this story that is not a tabloid

Who works hard every day to give the children all the tools they need to turn into successful adults?

growing mentally and emotionally?

 Who makes sure that the kids are growing mentally and emotionally?

stay fit mentally and physically

  trying to keep my promise to myself to stay fit mentally and physically as I age,

eating trail mix for lunch

social media and reality

 However, there is a big difference between what you see on social media and reality. 

It’s a salvage mission.

Frederick Gandolfo, MD


A Long Island native, Dr. Frederick Gandolfo graduated with a BS in biology from Fordham University in Bronx, NY.  He attended SUNY Stony Brook School of Medicine.  He completed internal medicine residency training at New York University.  He continued at NYU for gastroenterology fellowship and was awarded fellow of the year.  Dr. Gandolfo is board-certified in internal  and gastroenterology.


After practicing in a large group for several years, Dr. Gandolfo decided to go solo in 2018 and started his own practice, Precision Digestive Care, located in Huntington, NY

Dr. Gandolfo lives in Long Island with his wife and two children. Most of his time outside of medicine revolves happily around doing dad stuff, but he is also an amateur photographer, fitness enthusiatic, frustrated  writer, and empiricist at heart.

When Can I go home ?

https://retroflexions.com/confessions-of-a-gastroenterologist/when-can-i-go-home/ 

The importance of self-reliance and making things happen

Lower gastrointestinal bleeding (LGIB)

Lower gastrointestinal bleeding (LGIB) refers to blood loss of recent onset originating from a site distal to the ligament of Treitz [1,2].

 It is usually suspected when patients complain of hematochezia (passage of maroon or bright red blood or blood clots per rectum).

As a general rule of thumb, black tarry stool is usually caused by bleeding in the upper gastrointestinal tract (esophagus, stomach, duodenum) and red blood usually comes from the lower GI tract 

GI bleeding Rainbow photo (click the link and check the color)

Black tarry : Common causes include bleeding ulcers in the stomach or duodenum. 

Melenic stool is often described as glossy and sticky and has a characteristic horrible smell.

maroon stool, burgundy stool, and even mahogany stool.  Dark red blood is most often a sign of colonic bleeding,

Bright red blood is usually indicative of an anorectal source of bleeding such as a hemorrhoid or anal fissure. (BRBPR=Bright red bleeding per rectum ) 


adenocarcinoma

Parkinson’s

 . Parkinson’s affects approximately 1 in 1000 people in the general population. The peak onset is between 55 and 66 years of age however, a form of the disease has been known to occur in teenagers.