septic and organ dysfunction

 The septic circulatory lesion disrupts tissue oxygenation, alters the metabolic regulation of tissue oxygen delivery, and contributes to organ dysfunction. Microvascular and endothelial abnormalities contribute to the septic microcirculatory defect in sepsis.

Tetralogy of Fallot (TOF)

 What are the four defects of tetralogy?

Tetralogy of Fallot (TOF) | Nationwide Children's Hospital

Tetralogy of Fallot is a heart defect made up of four different heart problems: ventricular septal defect, overriding aorta, pulmonary stenosis and right ventricular hypertrophy. These problems result in cyanotic, or blue, skin on babies because of a lack of oxygen.

Lactic acidosis

 Lactic acidosis is a type of metabolic acidosis that occurs when lactic acids build up in your blood.

Your body produces more lactate when your tissues are deprived of oxygen. 

Lactate can also build up if your livers and kidneys aren't able to metabolize it efficiently. Jun 13, 2023

What causes your lactic acid to be high?

Lactic acidosis occurs when lactic acid production exceeds lactic acid clearance. 

The increase in lactate production is usually caused by impaired tissue oxygenation, either from decreased oxygen delivery or a defect in mitochondrial oxygen utilization.

Be careful - lactate can be elevated by unrelated conditions. 

Even though lactate produced in the presence of sepsis may not necessarily be the result of widespread hypoperfusion,

 lactate can be an indicator that anaerobic metabolism is taking place. Therefore, lactate is sensitive to sepsis but not specific to sepsis.

Finally, stopping exercise and allowing lactate to clear is the surefire way to get rid of excess lactate. 

Your body naturally gets rid of lactic acid through metabolism. 

Taking deep breaths, staying hydrated, and reducing exercise intensity are the best ways to maximize natural lactate clearance.Jan 31, 2022

causes of nausea

 Nausea causes

From sources across the web

GERD

Migraines

Motion sickness

Food poisoning

Pregnancy

Peptic ulcer disease

Food allergy

Gastroenteritis

Infections

Alcohol

Medications

Anxiety

Cancer

Diabetes

Dizziness

Ear problems

Gallstones

Appendicitis

Diet

Gastroparesis

Heart attack

Indigestion

Intestinal blockage

Irritable bowel syndrome