Showing posts with label Neurology. Show all posts
Showing posts with label Neurology. Show all posts

Saturday, August 31, 2024

dysarthria

 dysarthria

Dysarthria happens when the muscles used for speech are weak or are hard to control. Dysarthria often causes slurred or slow speech that can be difficult to understand.


Common causes of dysarthria include conditions that affect the nervous system or that cause facial paralysis. These conditions may cause tongue or throat muscle weakness. Certain medicines also can cause dysarthria.

Friday, August 23, 2024

Hyperalgesia

 (HY-per-al-JEE-zee-uh) An increased sensitivity to feeling pain and an extreme response to pain. Hyperalgesia may occur when there is damage to the nerves or chemical changes to the nerve pathways involved in sensing pain.

Tuesday, April 30, 2024

Headache

 Headache gets triggered by certain factors like bright light illumination, loud music, sunlight, lack of sleep, skipping meals, stress, refractive errors of the eyes, and insufficient water intake. The main way to reduce headaches quickly is to avoid the triggering factors. Drinking a cup of coffee which has caffeine as the content helps in good blood circulation to the brain and helps in relieving headaches. Drinking plenty of water and eating food frequently is also effective to treat headaches during periods. The application of ice packs or hot compresses, adequate sleep, avoiding stress, and regular exercises also reduce headaches. Medications containing caffeine, calcium channel blockers, and nonsteroidal anti-inflammatory drugs like acetaminophen, paracetamol, crocin, and nimesulide can be taken.

Sunday, August 6, 2023

Metabolic encephalopathy

 Metabolic encephalopathy is a problem in the brain. It is caused by a chemical imbalance in the blood. The imbalance is caused by an illness or organs that are not working as well as they should. It is not caused by a head injury. When the imbalance affects the brain, it can lead to personality changes.

What are signs and symptoms of metabolic encephalopathy?

Symptoms of Metabolic Encephalopathy Learning About Metabolic Encephalopathy | Kaiser Permanente

Symptoms may vary depending on the type of encephalopathy you have.

causes of encephalopathy

Delirium – Confused thinking and less attention span. It is a serious health concern and needs immediate attention.

Lethargy – Caused by a lack of nutrition and a high level of toxins in the body

Muscle weakness

Loss of memory or dementia

Difficulty in motor tasks such as walking, eating, writing, etc., is also known as ataxia

Illusions

Hallucinations

Decreased consciousness

Mood disorders

Breathing problems

Mental health issues such as depression, anxiety

Vision problems

Seizures

Sunday, July 9, 2023

Metabolic Encephalopathy

copy from : https://myhealth.alberta.ca/Health/aftercareinformation/pages/conditions.aspx?hwid=abo4850#:~:text=Metabolic%20encephalopathy%20is%20a%20problem,can%20lead%20to%20personality%20changes.

Learning About Metabolic Encephalopathy

What is metabolic encephalopathy?

Metabolic encephalopathy is a problem in the brain. It is caused by a chemical imbalance in the blood

The imbalance is caused by an illness or organs that are not working as well as they should. It is not caused by a head injury.When the imbalance affects the brain, it can lead to personality changes.  (Alter Mental status)It can also make it harder to think clearly and remember things.The problems may only last a short time if you get treatment right away. But this depends on the cause. If the imbalance has been building up because you've been sick for a long time, the mental changes may be more severe. They may also last longer.

What happens when you have this problem?When things are working right, your body has many ways to keep the chemicals in your blood in balance

For example, your liver and kidneys remove waste from your blood. The kidneys also help keep fluids and sodium in balanceAnd your pancreas makes insulin. It is a hormone that helps control the amount of sugar in your blood.

But the chemicals in your blood can get out of balance and damage parts of your body because of a medical problem.

This may be kidney or liver failure. 

Or it could be diabetes that isn't controlled well. When the imbalance affects the brain, normal thinking and behavior can change.

What are the symptoms?

Symptoms may include:

Confusion.

Problems with thinking and remembering.

Being grouchy and depressed.

Feeling drowsy.

Not being able to sleep.

Passing out (fainting) now and then.

How is it treated?

The doctor will try to find the illness that's causing the problem. The doctor may ask questions about your past health.

The doctor will also do tests to find what is causing the chemical imbalance and to see how severe it is.

The doctor may treat the organ system that's causing the problem. 

For example, if it's a kidney problem, you may have treatment to help your kidneys work better. 

If you have an infection, you may need antibiotics. If the doctor can't treat the cause of the problem, the doctor will treat the symptoms.

The doctor will carefully watch your blood chemicals to make sure that your treatment is being done safely.

Follow-up care is a key part of your treatment and safety. 

Be sure to make and go to all appointments, and call your doctor or nurse advice line (811 in most provinces and territories) if you are having problems. It's also a good idea to know your test results and keep a list of the medicines you take.

Current as of: June 6, 2022

Author: Healthwise Staff

Medical Review:Adam Husney MD - Family Medicine

Thursday, July 6, 2023

Alzheimer's Disease


Alzheimer's disease is a type of dementia that can cause people to be disoriented.

Alert and Oriented x1, x2, x3, and x4 in Dementia

https://www.verywellhealth.com/what-is-orientation-and-how-is-it-affected-by-dementia-98571 

Orientation is something healthcare providers check when screening for dementia and evaluating cognitive abilities.1

Merck Manual Professional Version. How to assess mental status.

 It refers to a person's level of awareness of self, place, time, and situation.

Healthcare providers score a person's orientation on a scale of 1 to 4. The higher the number, the better oriented a person is considered. For example, if you are fully alert and oriented, x4 will be noted.

When testing a person's orientation, a doctor asks standard questions that may seem like small talk. But these questions are useful for testing recent and longer-term memories.

Typical questions include:

What is your name?

Where are you?

What is the date?

What time is it?

What just happened to you?

This article includes information about what different levels of orientation mean and how they relate to Alzheimer's disease, dementia, and delirium.

Orientation Levels

In certain health assessments, orientation is sometimes referred to as "alert and oriented" (AO or A&O) or "awake, alert, and oriented" (AAO). It is usually followed by the multiplication symbol (x) and a number. For example, it may be written like "AOx3" or "AAOx4."

The level—x1, x2, x3, or x4—is a way of measuring the extent of a person's awareness.

Here's what the types of orientation mean:

  • Oriented to person: The person knows their name and usually can recognize significant others.
  • Oriented to place: The person knows where they are, such as the hospital, clinic, or town.
  • Oriented to time: The person knows the time of day, date, day of the week, and season.
  • Oriented to situation: They can explain why they are talking to the doctor.

Sometimes a person can answer some of this information, but not all. For example, they may know their name and the date but can't say where there are or why. In that case, it would be notated as x2.

In some circumstances, healthcare providers might only ask about person, place, and time. In that situation, x3 is the highest level of orientation tested. When a doctor includes questions about the situation, the highest level would then be x4.

In addition to the value (i.e., x3), a healthcare provider's notes should also include the specific questions asked and answers given.                                                                                                                            What Is the Memory Impairment Screen (MIS)? (verywellhealth.com)                                                                            

Wednesday, May 31, 2023

Causes of Spinal Stenosis

 Causes of Spinal Stenosis

Aging and Age-Related Changes in the Spine. Aging and age-related changes in the spine happen over a period of time and slowly cause loss of the normal structure of the spine. ...

Arthritis. Arthritis is also a common cause of spinal stenosis. ...

Inherited Conditions.

What is the most common cause of lumbar stenosis?

Lumbar Spinal Stenosis | Johns Hopkins Medicine

What causes lumbar spinal stenosis? 

The most common cause of spinal stenosis is osteoarthritis, the gradual wear and tear that happens to your joints over time.

 Spinal stenosis is common because osteoarthritis begins to cause changes in most people's spines by age 50.


Causes of osteoarthritis : Cause of Osteoarthritis

Osteoarthritis happens when the cartilage and other tissues within the joint break down or have a change in their structure. This does not happen because of simple wear and tear on the joints. Instead, changes in the tissue can trigger the breakdown, which usually happens gradually over time.Oct 1, 2019

Saturday, May 20, 2023

An intradural extramedullary tumor

An intradural extramedullary tumor is a spinal cord tumor that causes spinal cord compression — nerves in and around the spinal cord are compressed as the tumor grows in size. The vast majority of these tumors are benign and treated with surgery.Jun 2, 2017

What is the survival rate for intradural extramedullary tumor?

Another study also showed that most type of intradural tumor have 5-year survival rate >65%, this value was true except for intradural-extramedullary metastases which has mean survival time of 5–7,3 months [11,12]. In conclusion intradural tumor have great prognosis if the tumor is resected effectively.Apr 24, 2020

Friday, April 7, 2023

Hypoxia

 Hypoxia is low levels of oxygen in your body tissues. It causes symptoms like confusion, restlessness, difficulty breathing, rapid heart rate, and bluish skin. 

Many chronic heart and lung conditions can put you at risk for hypoxia. Hypoxia can be life-threatening


Hypoxemia can be caused by 

  1. lung and heart diseases
  2. congenital heart defects, and 
  3. medications that slow your breathing.
  4.  Traveling to a high altitude, where levels of oxygen are lower, can also cause hypoxemia.

Sunday, March 19, 2023

Brain Tumor

 Types of brain tumors

Primary brain tumors

  1. Astrocytomas
  2. Brain stem gliomas
  3. Ependymomas
  4. Oligodendrogliomas. 
There are other types of brain tumors that do not begin in glial tissue. Some of the most common are described below:

 Over 70,000 are primary brain tumors and the rest are metastatic brain cancer that has spread from cancer elsewhere in the body.(1) 

Fund raising only 9M per year 2M only use for research and only little fund goes into Glioblastoma(2).(a)(spread quickly),(symptom)(treatment plan)(coping )

Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testingresearch, and forensics(3) (4)

Research Outcome for oligo (5)

Brain Cancer Research

 Brain tumors are not rare, but research is badly underfunded.

Radiation : Gamma Knife and Cyber Knife

The Gamma Knife is an advanced radiation treatment for adults and children with small to medium brain tumors, abnormal blood vessel formations called arteriovenous malformationsepilepsytrigeminal neuralgia, a nerve condition that causes chronic pain, and other neurological conditions.

Cyberknife a non-invasive radiosurgery device called the CyberKnife that uses a robotic arm to deliver highly focused beams of radiation.


Palliative Care : 

Palliative care is specialized medical care for people living with a serious illness like a brain tumor as well as their families. The focus of palliative care is to provide support and relief from the symptoms and stress that a serious illness can cause.

Arteriovenous fistula (AVF)

Saturday, March 18, 2023

Parkinson’s

 . Parkinson’s affects approximately 1 in 1000 people in the general population. The peak onset is between 55 and 66 years of age however, a form of the disease has been known to occur in teenagers.

Saturday, December 24, 2022

Acute encephalopathy is reversible

 It is reversible when these abnormalities are corrected, with a return to baseline mental status. Acute encephalopathy may be further identified as toxic, metabolic, or toxic-metabolic.


types of encephalopathy

 There are several types of encephalopathy such as chronic traumatic encephalopathy (CTE) and hepatic encephalopathy.

Encephalopathy is often reversible with treatment. 
However, people with underlying chronic disorders such as liver disease are more likely to have repeated episodes of encephalopathy and need ongoing treatment.
Encephalopathy is often considered a complication of a primary problem such as alcoholic cirrhosis, kidney failure, or anoxia.

Acute encephalopathy

 Acute encephalopathy is characterized by an acute or subacute global, functional alteration of mental status due to systemic factors. 

Friday, December 23, 2022

What is the most common cause of encephalopathy?

 What is the most common cause of encephalopathy?

Encephalopathy may be caused by
infectious agent (bacteria, virus, or prion), 
metabolic or mitochondrial dysfunction, 
brain tumor or increased pressure in the skull, 
prolonged exposure to toxic elements (including solvents, drugs, radiation, paints, industrial chemicals, and certain metals), 
chronic progressive trauma.

Encephalopathy

 Encephalopathy can present a very broad spectrum of symptoms that range from mild, such as some memory loss or subtle personality changes, to severe, such as dementiaseizurescoma, or death.




The term encephalopathy, in most cases, is preceded by various terms that describe the reason, cause, or special conditions of the patient that leads to brain malfunction. For example, anoxic encephalopathy means brain damage due to lack of oxygen, and hepatic encephalopathy means brain malfunction due to liver disease.



The causes of encephalopathy are both numerous and varied. Examples of causes of encephalopathy include:

  • infectious (bacteria, viruses, parasites, or prions),
  • anoxic (lack of oxygen to the brain, including traumatic causes),
  • alcoholic (alcohol toxicity),
  • hepatic (for example, liver failure or liver cancer),
  • uremic (renal or kidney failure),
  • metabolic diseases (hyper- or hypocalcemia, hypo- or hypernatremia, or hypo- or hyperglycemic),
  • brain tumors,
  • toxic chemicals (mercury, lead, or ammonia),
  • alterations in pressure within the brain (often from bleeding, tumors, or abscesses), and
  • poor nutrition (inadequate vitamin B1 intake or alcohol withdrawal).

These examples do not cover all of the potential causes of encephalopathy but are listed to demonstrate the wide range of causes.

Although numerous causes of encephalopathy are known, the majority of cases arise from several major categories (some examples in parentheses):

Chronic traumatic encephalopathy (CTE)

 Chronic traumatic encephalopathy (CTE) ia progressive brain condition that's thought to be caused by repeated blows to the head and repeated episodes of concussion. It's particularly associated with contact sports, such as boxing or American football. 

Most of the available studies are based on ex-athletes.