Sunday, March 19, 2023

grueling

 gruel·ing

[ˈɡro͞oəliNG]
ADJECTIVE
  1. extremely tiring and demanding:
    "a grueling schedule"
  2. Dr Fredrick mentioned in the article that " After studying medicine and then doing a grueling residency and fellowship training for a total of ten years before even starting to see patients independently, it can be hard to say “I don’t know” when faced with certain questions".

Hubris is a killer. Fight it with humility!

 Hubris is a killer. Fight it with humility! 

Ascending colon CA (ASC CA)

  •  What are the signs and symptoms of ascending colon cancer?
  • Symptoms
  • A persistent change in your bowel habits, including diarrhea or constipation or a change in the consistency of your stool.
  • Rectal bleeding or blood in your stool.
  • Persistent abdominal discomfort, such as cramps, gas or pain.
  • A feeling that your bowel doesn't empty completely.
  • Weakness or fatigue.


Donation cell and tissue sample for research

https://www.oligonation.org/brain-cancer-research/biobank-research-platform/ 

Donation cell and tissue sample for research (1)

Donation link for cancer research

Donation link for Oligo cancer researchhttps://give.oligonation.org/give/306816/#!/donation/checkout

Brain Tumor

 Types of brain tumors

Primary brain tumors

  1. Astrocytomas
  2. Brain stem gliomas
  3. Ependymomas
  4. Oligodendrogliomas. 
There are other types of brain tumors that do not begin in glial tissue. Some of the most common are described below:

 Over 70,000 are primary brain tumors and the rest are metastatic brain cancer that has spread from cancer elsewhere in the body.(1) 

Fund raising only 9M per year 2M only use for research and only little fund goes into Glioblastoma(2).(a)(spread quickly),(symptom)(treatment plan)(coping )

Oligonucleotides are short DNA or RNA molecules, oligomers, that have a wide range of applications in genetic testingresearch, and forensics(3) (4)

Research Outcome for oligo (5)

Brain Cancer Research

 Brain tumors are not rare, but research is badly underfunded.

Radiation : Gamma Knife and Cyber Knife

The Gamma Knife is an advanced radiation treatment for adults and children with small to medium brain tumors, abnormal blood vessel formations called arteriovenous malformationsepilepsytrigeminal neuralgia, a nerve condition that causes chronic pain, and other neurological conditions.

Cyberknife a non-invasive radiosurgery device called the CyberKnife that uses a robotic arm to deliver highly focused beams of radiation.


Palliative Care : 

Palliative care is specialized medical care for people living with a serious illness like a brain tumor as well as their families. The focus of palliative care is to provide support and relief from the symptoms and stress that a serious illness can cause.

End stage renal disease (ESRD)

Arteriovenous fistula (AVF)

secondary hyperparathyroidism origin renal

Hyperparathyroidsim 

 An excess of the hormone made by four small glands in the neck (parathyroid glands).

  • Treatable by a medical professional
  • Requires a medical diagnosis 
  • Lab tests or imaging always required
  • Chronic: can last for years or be lifelong
An overactive parathyroid can be caused by an enlarged gland or as the result of another disease.
Often symptoms take a long time to develop. When they do occur, they include fragile bones, kidney stones, and excessive urination.
Treatments can include close monitoring of the condition or surgery.
Common: More than 200,000 US cases per year  

What is the typical symptom of hyperparathyroidism?
The most common symptoms of hyperparathyroidism are chronic fatigue, body aches, difficulty sleeping, bone pain, memory loss, poor concentration, depression, and headaches. Parathyroid disease also frequently leads to osteoporosis, kidney stones, hypertension, cardiac arrhythmias, and kidney failure.

CAD WO angina -coronary artery disease without angina

 coronary artery disease without angina 

HFpEF stands for Heart Failure with Preserved Ejection Fraction

Heart rate

 Heart rate-RRR